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Artificial Oocyte Activation (AOA)

Artificial Oocyte Activation (AOA) is a technique used during in vitro fertilization (IVF) to help increase the chances of fertilisation and embryo development.

It is a laboratory procedure that involves the use of specific chemicals or electrical stimulation to artificially activate the eggs.


AOA is typically used in cases where a couple has had repeated IVF failures or where there is a risk of failed fertilisation due to a sperm-egg activation problem.

This problem occurs when the sperm is unable to activate the egg, resulting in failed fertilisation.

AOA is also used in cases where the male partner has low sperm motility or reduced fertilizing ability.


During a normal fertilisation process, the sperm carries out an essential process called oocyte activation. This process helps the egg become fertilised and start developing into an embryo. However, in some cases, the sperm is unable to activate the egg, resulting in failed fertilisation.

AOA helps to bypass this problem by artificially activating the eggs in the laboratory. This can be done using chemicals or electrical stimulation.

Chemical activation involves the use of specific chemicals that mimic the sperm’s activation process.

Electrical activation, on the other hand, involves the use of small electrical pulses to activate the eggs.


The success rates of fertilisation with AOA can vary depending on the specific case and the clinic’s expertise.

Studies have shown that AOA can significantly increase the chances of fertilisation and embryo development in cases where there is a sperm-egg activation problem.

The success rates of fertilisation with AOA can range from 60% to 80%, depending on the specific technique used and the patient’s individual circumstances.

At Sago IVF Team North Cyprus, we successfully use Artificial Oocyte Activation as an effective method of improving fertilisation. It is important to note that AOA is not always necessary or recommended for all couples undergoing IVF.

The decision to use AOA should be made after a thorough consultation with a Sago Team fertility specialist. Contact Sago IVF Team in North Cyprus for free consultation and advice.

You may also be interested in Embryo DonationSperm FreezingIVF North Cyprus

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